Hormone-Refractory Prostate Cancer:
A Continuum of Diseases and Options
PRESENT LOCATION
Oliver Sartor, MD (1)
Professor of Medicine and Urology
Tulane Medical School
1430 Tulane Ave
New Orleans, LA 70112
Office Ph # 504-988-2750
Edited from PCRI Insights November, 2005 vol. 8 no.4
Introduction
It is possible that hormones can sometimes cure, but unfortunately, that seems to be true only in a minority of patients. Certainly if the disease has become significantly advanced at the time that hormonal therapy has begun, the probability of that cure is greatly diminished. There is clear data to indicate that the duration of response to hormonal therapy is inversely related to the volume of the disease. . . .
To read the complete article click "here".
Preventing / Treating Possible Chemotherapy Induced Peripheral Neuropathy
Introduction
There are two main toxicities to the extremities -- skin and nails and peripheral neuropathy - nerves. The definition list attempts to make the distinction clear.
Definitions
Nail Toxicity - this might manifest itself in various ways such as hyperpigmentation, splinter hemorrhage, subungual hematoma, cessation of nail growth, orange discoloration, etc. There is also
Onycholysis - the loosening or separation of a fingernail or toenail from its nail bed - manifested in 2-3% of patients(1,2).
Hand-Foot Syndrome - this is uncommon, but appears as a discoloration of the skin that progresses to blisters and shedding of outer layers of skin (desquamation.)
Peripheral Neuropathy (often abbreviated as P/N) - damage to the nerves that transmit signals from the extremities to the central nervous system. There is both motor neuropathy and sensory neuropathy. P/N can be dose limiting and can decrease the quality of life . . . .
To read the rest of the paper click "here".
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Hormone Refractory (HRPC)
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The Research of Bill Aishman
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